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How can cytoplasmic factors regulation integrin conformation?

How can cytoplasmic factors regulation integrin conformation? Integrin conformation-function connections: a model. A five-component unit demonstrating conformational modifications which can be of inside-out and outside-in integrin signalling. The I±-subunit is actually reddish as well as the I?-subunit in bluish. The figure demonstrates the 3 big conformational states which were recognized to date: sedentary (A), primed…
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